The role of the extracellular matrix in ovarian follicle development.

نویسندگان

  • Teresa K Woodruff
  • Lonnie D Shea
چکیده

Regulation of ovarian follicle development depends on endocrine- and paracrine-acting hormones, the 3-dimensional architecture of the follicle, and the physical rigidity of the surrounding tissue. These 3 forces are integrated throughout the life cycle of the follicle to ensure appropriate hormone secretion, differentiation of the somatic cells, and maturation of the oocyte. The process of in-follicle maturation provides a new tool for understanding ovarian follicle development under the influence of these factors.

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عنوان ژورنال:
  • Reproductive sciences

دوره 14 8 Suppl  شماره 

صفحات  -

تاریخ انتشار 2007